If you or someone at home has eczema-prone skin, you’ve probably heard the same advice on repeat: moisturise more. French dermatological skincare brand Uriage says that only gets you part of the way.
On 26 October 2026, Uriage launched its reformulated Xémose C8+ range in Singapore, sold at Watsons and Guardian. The body cream is priced at S$38.90.
The brand argues that the real problem is a weakened skin barrier rather than a shortage of moisture. That claim deserves a closer look before anyone spends money on it, and the science behind it is useful to understand even if you never pick up a tube.
Your Skin Has Cement
The brand describes ceramides as part of the “cement” that holds skin cells together. When there are enough of them, they help limit water loss and keep irritants out.
Uriage’s scientific slides go further. They split ceramides into 12 families, each tied to a specific job in the barrier, and they argue that both the quantity and the variety of ceramides matter. That point about variety is the basis for the whole C8+ idea. In the brand’s framing, atopic skin is short on several kinds of ceramide, so topping up a single kind won’t fully repair the barrier.
Why Eczema-Prone Skin Itches
In atopic-prone skin, the barrier becomes more permeable, so allergens, bacteria and other irritants get in more easily and contribute to dryness, itching and inflammation.
Uriage’s materials describe three linked barriers in total. The physical barrier is the ceramide wall. The microbiome barrier is the community of bacteria living on your skin. The brand’s slides say atopic skin tends to have less variety in that community and too much Staphylococcus aureus, a common bacterium. The immune barrier is how your skin’s defences react. In atopic skin, the slides describe an overactive inflammatory response that feeds the cycle of itching, redness and flare-ups.
That cycle explains why a moisturiser can feel lovely for an hour and still leave you scratching. Hydration on the surface doesn’t change how leaky the wall underneath is.
Eight Ceramides, Four Types
The headline ingredient in Xémose C8+ is a set of eight biomimetic ceramides, meaning lab-made ceramides designed to copy the structure of the ones your skin produces. The brand’s slides name four types among them: NP, NS, AP and EOP. Uriage says these were chosen for the specific needs of atopic skin.
For the microbiome and immune barriers, Uriage relies on its thermal water and two patented ingredients, TLR2-Regul and Chronoxin. The cream adds 10% shea butter. Uriage also said the formula contains no menthol, which is worth knowing if cooling ingredients tend to sting your skin.
Uriage confirmed that “atopic-prone” in its materials includes eczema-prone skin. The range is pitched at the whole family, “from babies and children to adults”.
“Atopic skin concerns go beyond surface dryness; they can affect sleep, comfort and overall quality of life,” said Sharon Teo, Brand Manager, Uriage Singapore.
What the Testing Shows
Uriage’s supporting documents describe a clinical study run under dermatological supervision on 22 people with sensitive, dry to very dry skin prone to atopy. Participants applied the Xémose C8+ Face cream twice a day. After 21 days, the brand reports that itching fell by 90%, redness by 69% and dryness by 76%. The assessor observed no skin reactions over that period.
The brand’s slides add a lab result. Ceramide levels in skin samples rose 1.5 times within one day of applying the C8+ balm, a different product from the creams on Singapore shelves. Uriage also claims 48-hour anti-itch and anti-recurrence efficacy for the cream.
Those numbers are encouraging, with two caveats to keep in mind. The trial involved 22 people, which is small. It also tested the face cream, a different product from the body cream on Singapore shelves. Treat the results as a promising start rather than settled proof.
Before You Buy
The brand’s own scientific slides call Xémose a “therapeutic adjunct” for skin prone to atopic eczema. In plain terms, Uriage designed it to support treatment, not to replace it. If your eczema is already under a doctor’s care, this range belongs alongside that plan rather than in place of it.
- Xémose C8+ Anti-itch Cleansing Oil, 500ml: S$55.90, a soap-free gel-oil that turns into a light foam in the shower
- Xémose C8+ Lipid-Replenishing Anti-itch Cream, 200ml: S$38.90, which Uriage describes as lightweight and quick-absorbing
- Xémose C8+ SOS Anti-Itch Mist, 200ml: S$33.90, a spray you can use without touching irritated skin
- Xémose C8+ Soothing Toner, 250ml: S$38.90, for extreme dryness on the face
For a first purchase, a smaller size makes the most sense.
Sensitive skin can react unpredictably even to gentle formulas, so the 50ml size at S$14.90, a Guardian exclusive, is a much cheaper test than a 500ml bottle that ends up unused in the cabinet. If you’re buying for a child, the oil-and-cream pair covers the shower and the moisturising step that follows it.
Even if Xémose C8+ never makes it into your basket, the ceramide explainer is worth keeping. Itchy, eczema-prone skin is a barrier problem as much as a moisture problem, so look for barrier-supporting care and talk to your doctor when the itching won’t settle. You can browse the full range on Uriage Singapore, or find it at Watsons and at Guardian, where the 50ml offer is running until 31 December 2026.
Photos and Visuals courtesy of Uriage.
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